An unofficial workaround until CD PROJEKT RED or Valve fix this properly. As soon as the 5.0 executable sees Wine, it turns off Streamline (DLSS SR/RR, DLSS-G, Reflex), ray tracing, path tracing and FSR frame generation. Everything here brings them back.
Important
The exe patch script supports only bin/x64_dx12/witcher3.exe 5.0.0.1090142 (patch 5.01c, Steam build 26238013, sha256 05948d72…bae0), 5.0.0.1048522 (patch 5.01, 2026-10-08, Steam build 2